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Job Description

Job Title Protein Chemist
Requirement ID 43019
Begin Date 9/28/09
Duration
Location Bothell,  WA 98021
Other Location
Description
We have an opportunity for an experienced protein chemist to participate in advancing Seattle Genetics’ industry-leading Antibody Drug Conjugate Technology in the Chemistry Department. We seek an individual who will enjoy working at the bench in a collaborative fashion alongside scientists with a variety of backgrounds and specialties. This position will allow a scientist to contribute to new antibody-drug conjugate programs from early discovery steps through IND submission.
 
Responsibilities:
  • Preparing antibody-drug conjugates (ADCs) at a variety of scales using established and experimental methodologies
  • Characterizing ADCs by a variety of techniques, including high resolution mass spectrometry and various chromatographic methods
  • Purifying antibodies and other recombinantly expressed proteins
  • Working with other scientists and departments in support of ADC discovery projects
  • Independent research to advance our understanding of ADC performance and improve future ADC programs


 

Required Skills Requirements:
- Ph.D. in Biochemistry, Chemistry, or a related field, or a B.S. degree with at least 8 years experience in the biopharmaceutical industry
- Experience with chemical modification of proteins
- Experience in the biochemical and biophysical characterization of purified proteins, including HPLC methods, SDS-PAGE, and spectroscopic methods
- Good communication and organizational skills and the ability to interface constructively with other scientists
- Desire to learn new techniques and expand one's skill set